Agnufem active substance is actually chaste tree (Vitex agnus-castus L.) fruit dry extract. Agnufem used for premenstrual syndrome illness aids. These ailments occur irritability, irritability, nervous tension, mood swings, breast hypersensitivity and spasmodic pains. 2. Before you Agnufem Agnufem Do not use - If you are allergic (hypersensitive) to the active substance or any of the other ingredients Agnufem material; - If the anamnesis is clear that in the past there have been or currently are symptoms of pituitary disorders; - If a woman is pregnant or feeding; - If the woman is younger than 18 years of age. Take special care with Agnufem need: Patients who are ill or suffering from estrogen dependent tumors before Agnufem administration should consult with your doctor. Patients taking dopamine receptor agonists and antagonists, estrogen and anti-estrogen before Agnufem administration should consult with your doctor (see section 4.5.). Children less than 18 years of age and adolescent drug use is not recommended. It is estimated that actually chaste fruit extract affects the hypothalamic - pituitary function, so in patients with pituitary disorders, the patients should consult with your doctor. In išskiriantiems prolactin pituitary tumors actually chaste fruit extract may mask the symptoms caused by the tumor. Taking other medicines Agnufem used in combination with a dopamine receptor agonists and antagonists, estrogen and anti-estrogen may decrease the effect of both drugs. Pregnancy and breast-feeding Before taking any medication, ask your doctor or pharmacist. Agnufem breast-feeding should not be used because it can reduce the amount of milk. The recommended dose of 1 tablet per day with liquid. The tablets are recommended for at least 3 months without interruption, as well as the time of menstruation.